CITRASATE™
Citrasate™, an exclusivity of Nipro Medical Europe, is an acid concentrate for dialysis that contains 0.8 mmol/l of citric acid and 0.3 mmol/l of acetate, instead of the traditional 3 mmol/l of acetic acid contained in standard acid concentrates.
The anticoagulant properties of citric acid, combined with a lower volume of acetate, improve the biocompatibility and dialysis adequacy while reducing the use of heparin.1-3
With our two manufacturing sites, MTN in Germany and NRS in Spain, we can ensure a continuous supply, offering a wide range of Citrasate to an extended geographical area.
Available in mixing ratio 1:44, the Citrasate comes in bags, canisters, politainers (soft container), and large volume bag-in-box or rigid containers* – that latter of which links directly to dialysis machines.
- Unique citric acid concentrate with a reduced amount of acetate
- Improved biocompatibility and dialysis adequacy
- Variety of single-use or multiple-use container types and sizes to match different needs
- Easy to handle, store, and dispose of
- Large volume bag-in-box and rigid containers to reduce environmental impact and minimize handling
* Availability of products might vary per country. Please contact your local Nipro representative for specifications, minimum order quantities, and availability.
Footnotes
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Ahrenholz P et al. Heparin reduction and improved compatibility using citrate enriched dialysate. EDTA Congress, Paris 2012, Abstract and poster FP 434 BIOCOMPATIBLE Reduce heparin
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Kossmann RJ et al. Fifty-five percent heparin reduction is safe with Citrasate dialysate in chronic dialysis Patients. ASN Renal week Meeting, 2006, Abstract No. 708 Reduce heparin
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Sands JJ et al. Effects of citrate acid (Citrasate) on Heparin N Requirements and hemodialysis Adequacy: A multicenter, prospective noninferiority trial. Blood. Purif. 2012;33:199-204
Downloads
Manuals and/or IFU's
| Product type | Location |
|---|---|
| Bags, Politainer/soft canister, Container/tank, Bag in Box (version nov-2021) | Germany (MTN) |
| Canister (all) (version nov-2021) | Germany (MTN) |
| NiproBag (version may-2023) | Spain (NRS) |
| Octabin/bag in box | Spain (NRS) |
| NiproSol (version jul-21) | Spain (NRS) |
| NiproTank-D (version mar-21) | Spain (NRS) |
| Canister multiple use | Spain (NRS) |
