Emergency medications play a vital role in preserving life during critical medical events such as acute myocardial infarction, cardiac arrest, and severe cardiac arrhythmias.
Emergency drugs are packed in a diverse range of containers. Nipro offers a selective portfolio of high-quality primary packaging solutions that contribute to reliable fill-finish operations, smooth integration with auto-injection devices, and stable storage.
D2F™ Pre-Fillable Glass Syringes
Trusted, ready-to-use packaging solutions for fast time to market
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Readily available trial samples
[to facilitate a fast start of tests]
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D2F™ Tub&Nest compatible with prevailing fill-finish lines
[fast to run and easy integration]
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Proven technology
[D2F™ Syringes used widely by pharmaceutical leaders]
Precise syringe attributes for fast and stable fill-finish operations
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High dimensional quality
[reliable filling and plunger fit]
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Strong mechanical durability1
[minimized risk of breakage]
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High cosmetic quality
[lower risk of rejection at final inspection]
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Strong container closure integrity (CCI)2
[reduced risk of leakage]
Smoother and safer manual administration
-
Smooth plunger movement3
[low variability in break-loose and glide force]
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Individual needle verification for precise penetration
[100% inspection of needle angularity and tip | needle siliconization precisely monitored]
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Safer handling
[firm connection to standard hypodermic needles4 | proper torque and pull-off force, needle stick injury5 prevention system]
Accurate fit and smooth functionality with auto-injectors
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Accurate dimensions6
[enable precise integration and functionality with pen systems]
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Consistent inner diameter and wall thickness of glass barrel7
[to support accurate dose delivery]
- Strong mechanical durability6,7
[for stable use with pen injection systems]
Comprehensive service level and documentation
-
Data for efficient acceptance of delivered goods
[certificate of conformity | certificate of sterility]
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On-site customer support
[smooth integration of RTU syringes on high-speed filling lines]
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Regulatory data for standards compliance
[physical and chemical properties compliant with pharmacopeia]
-
Drug master file data
[registered with FDA, Health Canada, NMPA | easy procedure to receive LOA]
Footnotes
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Glass tubing with consistent inner diameter, Laser-based cutting, precise forming process, 100% in-line camera inspections of dimensional parameters
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100% in-line camera inspections of dimensional (inner diameter of syringe barrel, syringe tip) and physical (closure pull-off force) parameters
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Silicone-influenced parameters were carefully tested (break-loose force, glide force, particle levels)
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ISO 11040-4 Luer cone breakage resistance compliant
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Compatible with safety systems
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100%, in-line camera inspection for a broad range of dimensional specifications (such as shoulders, length, neck)
-
High-quality glass tubing
Recommended Syringe Range
| Specifications | |
|---|---|
| Quality level | ENABLE |
| Syringe type | Staked needle |
| Syringe size (ml) | 0.5 | 1 long |
| Closure material | 4800 GS | FM27 |
| Stopper material supplier | Aptar 6422 | West PH 701 | Datwyler FM 257 |
| Silicone amount (mg) | 0.7 per syringe |
| Flange type | Cut flange |
| Staked needle | 27G ½“ - thin wall |
| Options | Backstop | Safety system |
Related products
Glass Vials
Contributes to stable fill-finish process
-
High dimensional quality8
[for efficient fill-finish]
-
Strong mechanical durability8
[reduced risk of vial breakage during filling]
-
High cosmetic quality8
[lower risk of rejects at final inspection]
Standardized packaging solutions for a fast time-to-market
-
Readily available trial samples
[to test packaging]
-
D2F™ Tub&Nest configurations compatible with prevailing fill-finish lines
[fast to run and easy integration]
-
Proven technology
[D2F™ vials used widely by pharmaceutical leaders]
Standard service level and documentation
-
Data for efficient acceptance of delivered goods
[certificate of conformity | certificate of sterility]
-
On-site customer support
[smooth integration of RTU vials on high-speed filling lines]
-
Regulatory data for standards compliance
[physical and chemical properties compliant with pharmacopeia]
-
Drug Master file data
[registered with FDA, Health Canada, NMPA | easy procedure to receive LOA]
Footnotes
8. High-quality glass tubing, 100% in-line visual inspection of cosmetic and dimensional parameters
Recommended Vial Range
| Specifications (for parenteral drug products) |
|
|---|---|
| Quality level | ENABLE |
| Vial size (ml) | 2R to 30R |
| Glass color | Clear |
| Silk screening | |
| Packaging | Bulk | D2F™ |
| Specifications (for nasal drug products) |
|
|---|---|
| Quality level | ENABLE |
| Unit-dose™ micro-vial size (ml) | 0.35 to 0.5 |
| Glass color | Clear |
| Silk screening | |
| Packaging | Bulk |
| Compatibility | Nasal injection device |
Related products
Glass Cartridges
Designed for Precise Integration into Pen Systems
-
Accurate dimensions15
[enable precise integration and functionality with pen systems]
-
Consistent inner diameter and wall thickness of glass barrel16
[to support accurate dose delivery]
- Strong mechanical durability15,16
[for stable use with pen injection systems]
Excellent Cosmetic Quality
- High cosmetic quality17
[for reduced risk of rejects due to glass defects]
- Pristine appearance
[contributes to higher acceptance by end-user]
Extended Data Package for Fast Acceptance of Goods
-
Fast acceptance of delivered goods is facilitated
[CoA18 | CoS19 | additional certificate upon request]
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Regulatory data confirms compliance with standards
[physical & chemical properties | compliant to pharmacopeia | level of sub-visible particles | risk analysis]
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Drug Master File related data
[for FDA, Health Canada, and NMPA | easy procedure to receive LoA20]
Footnotes
15. 100%, in-line camera inspection for a broad range of dimensional specifications (such as shoulders, length, neck)
16. High-quality glass tubing
17. 100%, in-line camera inspection for a broad range of cosmetic parameters (such as stones, knots, inclusions, scratches, particles)
18. Certificate of Analysis
19. Certificate of Sterility
20. Letter of Access/Authority
Recommended Cartridge Range
| Specifications | |
|---|---|
| Quality level | ENHANCE |
| Cartridge size (ml) | 1.8 | 3.0 |
| Glass color | Clear |
| Ceramic | |
| Packaging | Bulk |
Related products
Trusted Packaging Solutions for Emergency Drug Delivery
Need help?
Get in touch
For information regarding Nipro products, services, and resource material:
| Give us a call +32 15 263 500 |
E-mail us [email protected] |
| Submit a detailed inquiry: Contact per expertise |
View our manufacturing locations: Our global network |