For the highest quality requirements
eNhance NSV51 glass tubing is an excellent choice for primary pharmaceutical containers of the highest quality that must meet the requirements of highly sophisticated drug products.
eNhance NSV51 glass tubing is carefully inspected for a wide range of cosmetic parameters. Particle levels are minimized by an in-line air flushing system. Camera inspections are 100% in-line and supported by statistical process control. The entire process is streamlined to yield optimal cosmetic quality.
Our state-of-the-art, 100% in-line camera system controls an extensive range of dimensional attributes with very tight tolerances. This ensures glass tubing with highly consistent wall thickness and inherent strong mechanical durability, and it is complemented by high dimensional consistency for demanding primary containers.
Very tight dimensional and cosmetic AQLs reflect the exceptional container quality of eNhance NSV51 glass tubing. All drawing sites are ISO 15378 (including 9001) certified. This glass tubing is compliant with leading Pharmacopoeias (EP, USP, JP). It fulfills ASTM 438-92 and meets the requirements for hydrolytic resistance and arsenic extraction.
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Fast and reliable converting line performance
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Very strict cosmetic parameters
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Highly precise dimensional attributes
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Meeting the highest regulatory and quality requirements
Glass type | Expansion | Hydrolytic resistance | Color |
---|---|---|---|
Borosilicate | 51 | Type I | Clear |
Outer diameter | Wall thickness | Length |
---|---|---|
6.0-19.9 mm | 0.45-1.10 mm | 1,400-1,675 mm |
20.0-27.9 mm | 0.55-1.70 mm | 1,400-1,675 mm |
28.0-30.0 mm | 0.90-1.70 mm | 1,400-1,675 mm |
Symbol | Value* | |
---|---|---|
SiO2 | 74.5% | |
B2O3 | 11% | |
Al2O3 | 6% | |
Na2O | 7.0% | |
K2O | 0.8% | |
CaO | 0.4% |
Property | Value* |
---|---|
Working Point | 1,090 °C |
Softening Point | 788 °C |
Anneal Point | 568 °C |
Coefficient of Thermal Expansion | 51 cm/cm x 10-7/°C |
Density | 2.31 g/cm³ |
Standard | Classification |
---|---|
USP Powdered Durability – Chapter <660> Current Edition, Vol. 1 | Type I |
USP Powdered Durability – Chapter <660> Current Edition, Vol. 1 EP Hydrolytic Resistance – Chapter 3.2.1, Current Edition, Vol. 1 | Type I |
JP Containers for Injection – Current Edition | Passes |
ISO 695 Alkali Resistance | Class A2 |
DIN 12116 Acid Resistance | Class S1 |
Standard | Status |
---|---|
Arsenic extraction requirement according to USP and EP | Compliant |
Heavy metal requirements set forth in EU Packaging, Packaging Waste Directive 94/62/EC, and CONEG Toxics in Packaging regulations | Compliant |
Frequently Asked Questions (FAQs)
The "thermal expansion coefficient" typically ranges between 5.0 × 10^-6 /°C and 10.0 × 10^-6 /°C, depending on the specific type of glass. This coefficient indicates the extent to which a unit length of glass will expand or contract with a one-degree change in temperature, expressed in terms of per degree Celsius (°C).
In the context of glass used for pharmaceutical packaging, hydrolytic resistance is a crucial property. It indicates the glass's ability to maintain its integrity and prevent leaching of ions or other substances into the contained pharmaceutical product when in contact with water or aqueous solutions. Glass with high hydrolytic resistance is less prone to chemical interactions and is therefore preferred for packaging sensitive pharmaceutical formulations.
Amber-colored glass tubing is often used to manufacture vials, ampoules, and bottles for packaging light-sensitive medications. The amber color of the glass provides protection against ultraviolet (UV) light, which is known to degrade light-sensitive pharmaceuticals, thus ensuring the stability and potency of the enclosed medications.
For information regarding Nipro products, services, and resource material:
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E-mail us pharmapackaging@nipro-group.com |
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