Nipro NSV51 glass tubing with cerium is backed by decades of expertise in manufacturing a broad range of premium quality glass tubing. We are an experienced global supplier that also offers professional advice on dimensional and cosmetic specifications, necessary tolerances, and special surface treatments that are best suited for your primary container – and ultimately – your drug product.

Our global manufacturing network, with a total capacity of >90,000 metric tons, is one of the largest in the glass tubing industry. Our sites are ISO 9001, ISO 15378, and OHSAS 18001 certified and our premium glass tubing complies to the European Pharmacopoeia, Japanese Pharmacopeia, and United States Pharmacopoeia.

  • Outstanding chemical resistance
  • Material of choice for pre-fillable syringes, vials, and cartridges
  • Extensive cosmetic and dimensional inspections to meet stringent quality requirements
  • USP, EP, JP compliant
  • Multiple plants on three continents
  • State of the art production sites are ISO 9001, ISO15378, OHSAS 18001 certified
Specifications
General
Glass type Expansion Hydrolytic resistance Color
Borosilicate 51 Type I Clear
Standard dimensions
Outer diameter Wall thickness Length
6.0-19.9 mm 0.45-1.10 mm 1,400-1,675 mm
20.0-27.9 mm 0.55-1.70 mm 1,400-1,675 mm
28.0-30.0 mm 0.90-1.70 mm 1,400-1,675 mm
Tolerances available upon request
Chemical composition
Symbol Value*
SiO2 73.5 %
B2O3 11 %
Al2O3 6 %
Na2O 7 %
K2O 0.8 %
CaO 0.4 %
CeO2 1 %
* Typical average values
Physical properties
Property Value*
Softening Point 784 °C
Anneal Point 568 °C
Strain Point 518 °C
Coefficient of Thermal Expansion 51 cm/cm x 10-7/°C
Density 2.31 g/cm³
* Typical average values
Chemical durability
Standard Classification
USP Powdered Durability – Chapter <660> Current Edition, Vol. 1 Type I
USP Powdered Durability – Chapter <660> Current Edition, Vol. 1 EP Hydrolytic Resistance – Chapter 3.2.1, Current Edition, Vol. 1 Type I
JP Containers for Injection – Current Edition Passes
ASTM E438-92 Type I, Class B
ISO 719 HGB 1
ISO 695 Alkali Resistance Class A2
DIN 12116 Acid Resistance Class S1
Arsenic extraction & Heavy metal requirements
Standard Status
Arsenic extraction requirement according to USP and EP Compliant
Heavy metal requirements set forth in EU Packaging, Packaging Waste Directive 94/62/EC, and CONEG Toxics in Packaging regulations Compliant
Downloads
Glass Tubing
Pharmaceutical Packaging
Brochures

Frequently Asked Questions (FAQs)

How does the coefficient of expansion of glass affect its suitability for pharmaceutical packaging?

The "thermal expansion coefficient" typically ranges between 5.0 × 10^-6 /°C and 10.0 × 10^-6 /°C, depending on the specific type of glass. This coefficient indicates the extent to which a unit length of glass will expand or contract with a one-degree change in temperature, expressed in terms of per degree Celsius (°C).

What does "glass hydrolytic resistance" mean?

In the context of glass used for pharmaceutical packaging, hydrolytic resistance is a crucial property. It indicates the glass's ability to maintain its integrity and prevent leaching of ions or other substances into the contained pharmaceutical product when in contact with water or aqueous solutions. Glass with high hydrolytic resistance is less prone to chemical interactions and is therefore preferred for packaging sensitive pharmaceutical formulations.
 

Why is amber-colored glass tubing used for pharmaceutical packaging?

Amber-colored glass tubing is often used to manufacture vials, ampoules, and bottles for packaging light-sensitive medications. The amber color of the glass provides protection against ultraviolet (UV) light, which is known to degrade light-sensitive pharmaceuticals, thus ensuring the stability and potency of the enclosed medications.
 

Need help?
Get in touch

For information regarding Nipro products, services, and resource material: 

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+32 15 263 500
E-mail us
pharmapackaging@nipro-group.com
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